Tag Archives: SARSCoV2

Protein OCLN discovered to play essential function in SARS-CoV-2 cell-to-cell transmission

In a latest research revealed within the journal PNAS, researchers demonstrated that the tight junction (TJ) protein occludin (OCLN) is vital for extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S)-mediated, direct cell-to-cell transmission inside a number. Research: Tight junction protein occludin is an internalization issue for SARS-CoV-2 an infection and mediates virus cell-to-cell transmission. […]

How SARS-CoV-2 Omicron subvariants have developed to evade host T-cell immunity

In a current article revealed within the journal PNAS, researchers examine whether or not the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants of concern (VOCs), particularly Omicron, have developed to evade CD8+ T cell-mediated immunity much like how these VOCs have acquired mutations inside the spike (S) protein to withstand neutralizing antibodies (nAbs). […]

Examine finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

In a current research posted to the bioRxiv* preprint server, researchers in the US assess the efficacy of the human surfactant protein A (SP-A) in opposition to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity. Examine: Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial Cells. Picture Credit score: Filip Fuxa / Shutterstock.com *Necessary discover: […]

SARS-CoV-2 BA.1 and BA.2 breakthrough infections doubtless shield in opposition to BA.4 an infection

*Vital discover: medRxiv publishes preliminary scientific experiences that aren’t peer-reviewed and, due to this fact, shouldn’t be considered conclusive, information scientific observe/health-related conduct, or handled as established data. In a current research posted to the medRxiv* preprint server, researchers in Australia report the sturdiness and dynamics of recalled extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […]

Understanding components that affect mother and father’ selections about SARS-CoV-2 vaccination for his or her kids

For fogeys, the choice to vaccinate their children in opposition to SARS-CoV-2 is advanced, influenced by scientific proof, political and social pressures, and views about particular person versus collective advantages of vaccination, based on a brand new research printed in CMAJ (Canadian Medical Affiliation Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221401. Researchers carried out a qualitative research with in-depth interviews […]

Pan-vaccine antigen technique confers safety in opposition to cross-clade SARS-CoV-2 variants, together with vaccine-resistant Omicron variants

In a current article revealed in Science Translational Drugs, researchers developed a novel pan-vaccine antigen (Span)-based subunit vaccine in opposition to coronavirus illness 2019 (COVID-19). Utilizing a mouse mannequin, in addition they demonstrated that this vaccine formulation conferred safety in opposition to a number of clades of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Research: […]

Examine finds bebtelovimab remedy lacks efficacy in sufferers contaminated with SARS-CoV-2 Omicron subvariants

In a latest research posted to the medRxiv* preprint server, researchers assessed the affect of bebtelovimab (BEB) monoclonal antibody (MAb) within the remedy of high-risk extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant-infected sufferers. Examine: Lack of effectiveness of Bebtelovimab Monoclonal Antibody Amongst Excessive-Threat Sufferers with SARS-Cov-2 Omicron Throughout BA.2, BA.2.12.1 and BA.5 Subvariants […]

SARS-CoV-2 seroprevalence in home cats has elevated over time

In a latest research posted to the bioRxiv* preprint server, researchers evaluated extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission amongst home cats in the UK (UK). Examine: Rising SARS-CoV-2 Seroprevalence and Patterns of Cross-Variant Antibody Neutralization in UK Home Cats. Picture Credit score: Gunnar Rathbun/Shutterstock Cats have been in shut contact with animals (wild […]