An infection-induced cognitive decline: Mechanisms and potential therapies

Organic brokers threaten individuals’s life by way of alternative ways, one among which lies within the impairment of cognition. It’s believed cognitive decline could consequence from organic brokers mediated neuron harm immediately, or from the activation of the host immune response to eradicate the pathogen. Nonetheless, there may be restricted proof for direct linkage between infections and cognitive decline.

The authors of this text give attention to the mechanisms of how completely different organic viruses, or their induced systemic and native irritation, hyperlink to the cognitive impairment, specializing in the roles of activated microglia and several other molecular pathways mediated neurotoxicity.

Highlights

• An infection induced cognitive decline are persistent menace to individuals’s well being.
• An infection induces neurotoxicity and neuroinflammation which contributes to cognitive decline.
• Focusing on CDK5 or different important pathway could present new options to alleviate an infection induced cognitive decline.

Supply:

Journal reference:

Du, C., et al. (2023). Biosafety and psychological well being: Virus induced cognitive decline. Biosafety and Well being. doi.org/10.1016/j.bsheal.2023.04.002.